Caffeine, citrated
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971 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 42 | 2 | — | 5 | 46 | 95 |
| Apnea | D001049 | HP_0002104 | R06.81 | 1 | 4 | 6 | 5 | 12 | 27 |
| Obesity | D009765 | EFO_0001073 | E66.9 | 5 | 4 | 3 | 1 | 16 | 26 |
| Premature birth | D047928 | EFO_0003917 | O60 | 1 | 3 | 7 | 3 | 13 | 25 |
| Headache | D006261 | HP_0002315 | R51 | 2 | 1 | 7 | 4 | 9 | 22 |
| Neoplasms | D009369 | — | C80 | 5 | 1 | — | 1 | 8 | 15 |
| Migraine disorders | D008881 | EFO_0003821 | G43 | — | 2 | 8 | 2 | 4 | 15 |
| Syndrome | D013577 | — | — | — | — | 1 | 1 | 12 | 14 |
| Wounds and injuries | D014947 | — | T14.8 | 1 | 1 | — | 2 | 10 | 13 |
| Affect | D000339 | — | — | — | — | — | 1 | 12 | 13 |
Show 57 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Covid-19 | D000086382 | — | — | 1 | 1 | 1 | — | 9 | 12 |
| Heart failure | D006333 | HP_0001635 | I50 | — | — | 1 | — | 10 | 11 |
| Hiv infections | D015658 | EFO_0000764 | B20 | 3 | 1 | 2 | — | 4 | 10 |
| Weight loss | D015431 | HP_0001824 | — | — | 2 | 2 | — | 7 | 9 |
| Coronary artery disease | D003324 | — | I25.1 | — | — | 2 | — | 7 | 9 |
| Hypoxia | D000860 | HP_0012418 | R09.02 | 4 | 2 | 1 | — | 2 | 8 |
| Multiple sclerosis | D009103 | EFO_0003885 | G35 | — | 2 | 1 | — | 4 | 7 |
| Myocardial ischemia | D017202 | EFO_1001375 | I20-I25 | — | — | 2 | — | 5 | 7 |
| Atrial fibrillation | D001281 | EFO_0000275 | I48.0 | — | — | 1 | — | 5 | 6 |
| Sclerosis | D012598 | — | — | 1 | 1 | 1 | — | 3 | 6 |
Show 55 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Sleep initiation and maintenance disorders | D007319 | — | F51.01 | 2 | 3 | — | — | 19 | 23 |
| Diabetes mellitus | D003920 | HP_0000819 | E08-E13 | 1 | 1 | — | — | 12 | 14 |
| Depression | D003863 | — | F33.9 | — | 2 | — | — | 9 | 11 |
| Type 1 diabetes mellitus | D003922 | EFO_0001359 | E10 | — | 3 | — | — | 8 | 11 |
| Stroke | D020521 | EFO_0000712 | I63.9 | 2 | 2 | — | — | 7 | 10 |
| Depressive disorder | D003866 | EFO_1002014 | F32.A | — | 1 | — | — | 7 | 8 |
| Overweight | D050177 | — | E66.3 | 2 | 1 | — | — | 5 | 7 |
| Obstructive sleep apnea | D020181 | EFO_0003918 | G47.33 | — | 1 | — | — | 5 | 6 |
| Atopic dermatitis | D003876 | EFO_0000274 | L20 | 4 | 1 | — | — | 1 | 6 |
| Dermatitis | D003872 | HP_0011123 | L30.9 | 4 | 1 | — | — | 1 | 6 |
Show 57 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Drug interactions | D004347 | — | — | 11 | — | — | — | 3 | 14 |
| Hypotension | D007022 | EFO_0005251 | I95 | 1 | — | — | — | 5 | 6 |
| Substance-related disorders | D019966 | EFO_0003890 | F13 | 2 | — | — | — | 3 | 5 |
| Psoriasis | D011565 | EFO_0000676 | L40 | 5 | — | — | — | — | 5 |
| Prostatic neoplasms | D011471 | — | C61 | 1 | — | — | — | 4 | 5 |
| Arthritis | D001168 | HP_0001369 | M05-M14 | 3 | — | — | — | 2 | 5 |
| Acute kidney injury | D058186 | HP_0001919 | N17 | 1 | — | — | — | 4 | 5 |
| Pharmacokinetics | D010599 | — | — | 2 | — | — | — | 2 | 4 |
| Chronic pain | D059350 | HP_0012532 | — | 1 | — | — | — | 3 | 4 |
| Metabolism | D008660 | GO_0008152 | — | 2 | — | — | — | 2 | 4 |
Show 50 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Fatigue | D005221 | HP_0012378 | R53.83 | — | — | — | — | 19 | 19 |
| Sleep | D012890 | GO_0030431 | — | — | — | — | — | 13 | 13 |
| Sleep deprivation | D012892 | — | F51.12 | — | — | — | — | 12 | 12 |
| Sleep wake disorders | D012893 | — | G47 | — | — | — | — | 11 | 11 |
| Placebos | D010919 | — | — | — | — | — | — | 10 | 10 |
| Urinary incontinence | D014549 | HP_0000020 | R32 | — | — | — | — | 10 | 10 |
| Hypertension | D006973 | EFO_0000537 | I10 | — | — | — | — | 10 | 10 |
| Overactive urinary bladder | D053201 | EFO_1000781 | N32.81 | — | — | — | — | 9 | 9 |
| Epilepsy | D004827 | EFO_0000474 | G40.9 | — | — | — | — | 9 | 9 |
| Seizures | D012640 | HP_0002069 | G40.4 | — | — | — | — | 9 | 9 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Safety
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25,278 adverse events reported
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